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Elucidation of the Binding Orientation in α2,3- and α2,6-Linked Neu5Ac-Gal Epitopes toward a Hydrophilic Molecularly Imprinted Monolith

[Image: see text] N-Acetylneuraminic acid and its α2,3/α2,6-glycosidic linkages with galactose (Neu5Ac-Gal) are major carbohydrate antigen epitopes expressed in various pathological processes, such as cancer, influenza, and SARS-CoV-2. We here report a strategy for the synthesis and binding investig...

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Detalles Bibliográficos
Autores principales: Huynh, Chau Minh, Mavliutova, Liliia, Sparrman, Tobias, Sellergren, Börje, Irgum, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666243/
https://www.ncbi.nlm.nih.gov/pubmed/38027366
http://dx.doi.org/10.1021/acsomega.3c06836