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Machine Learning Approaches Identify Chemical Features for Stage-Specific Antimalarial Compounds

[Image: see text] Efficacy data from diverse chemical libraries, screened against the various stages of the malaria parasite Plasmodium falciparum, including asexual blood stage (ABS) parasites and transmissible gametocytes, serve as a valuable reservoir of information on the chemical space of compo...

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Detalles Bibliográficos
Autores principales: van Heerden, Ashleigh, Turon, Gemma, Duran-Frigola, Miquel, Pillay, Nelishia, Birkholtz, Lyn-Marié
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666252/
https://www.ncbi.nlm.nih.gov/pubmed/38027377
http://dx.doi.org/10.1021/acsomega.3c05664