New Pyrazole-Clubbed Pyrimidine or Pyrazoline Hybrids as Anti-Methicillin-Resistant Staphylococcus aureus Agents: Design, Synthesis, In Vitro and In Vivo Evaluation, and Molecular Modeling Simulation

[Image: see text] Two hybrid series of pyrazole-clubbed pyrimidines 5a–c and pyrazole-clubbed pyrazoline compounds 6a,b and 7 were designed as attractive scaffolds to be investigated in vitro and in vivo for antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and Pseudo...

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Detalles Bibliográficos
Autores principales: Mansour, Basem, El-Sherbeny, Magda A., Al-Omary, Fatmah A. M., Saber, Sameh, Ramadan, Heba A., El-Baz, Ahmed M., Mourad, Ahmed A. E., Abdel-Aziz, Naglaa I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666275/
https://www.ncbi.nlm.nih.gov/pubmed/38027391
http://dx.doi.org/10.1021/acsomega.3c06936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666275/
https://www.ncbi.nlm.nih.gov/pubmed/38027391
http://dx.doi.org/10.1021/acsomega.3c06936

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