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Novel Calcium-Binding Motif Stabilizes and Increases the Activity of Aspergillus fumigatus Ecto-NADase

[Image: see text] Nicotinamide adenine dinucleotide (NAD) is an essential molecule in all kingdoms of life, mediating energy metabolism and cellular signaling. Recently, a new class of highly active fungal surface NADases was discovered. The enzyme from the opportunistic human pathogen Aspergillus f...

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Detalles Bibliográficos
Autores principales: Ferrario, Eugenio, Kallio, Juha P., Strømland, Øyvind, Ziegler, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666276/
https://www.ncbi.nlm.nih.gov/pubmed/37934975
http://dx.doi.org/10.1021/acs.biochem.3c00360