Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase

[Image: see text] Intracellular leucine aminopeptidases (PepA) are metalloproteases from the family M17. These enzymes catalyze peptide bond cleavage, removing N-terminal residues from peptide and protein substrates, with consequences for protein homeostasis and quality control. While general mechan...

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Detalles Bibliográficos
Autores principales: Simpson, Martha Clementine, Harding, Christopher John, Czekster, Ricardo Melo, Remmel, Laura, Bode, Bela E., Czekster, Clarissa Melo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666288/
https://www.ncbi.nlm.nih.gov/pubmed/37924287
http://dx.doi.org/10.1021/acs.biochem.3c00420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666288/
https://www.ncbi.nlm.nih.gov/pubmed/37924287
http://dx.doi.org/10.1021/acs.biochem.3c00420

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