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Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase

[Image: see text] Intracellular leucine aminopeptidases (PepA) are metalloproteases from the family M17. These enzymes catalyze peptide bond cleavage, removing N-terminal residues from peptide and protein substrates, with consequences for protein homeostasis and quality control. While general mechan...

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Detalles Bibliográficos
Autores principales:	Simpson, Martha Clementine, Harding, Christopher John, Czekster, Ricardo Melo, Remmel, Laura, Bode, Bela E., Czekster, Clarissa Melo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666288/ https://www.ncbi.nlm.nih.gov/pubmed/37924287 http://dx.doi.org/10.1021/acs.biochem.3c00420

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