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MicroRNA-21 promotes head and neck squamous cell carcinoma (HNSCC) induced transition of bone marrow mesenchymal stem cells to cancer-associated fibroblasts

BACKGROUND: Most patients diagnosed with head and neck tumor will present with locally advanced disease, requiring multimodality therapy. Bone marrow-derived mesenchymal stromal cells (BMSCs) respond to a variety of tumor cell-derived signals, such as inflammatory cytokines and growth factors. As a...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Zhou, Zhengyu, Lin, Wenchao, Qian, Yechun, He, Shifang, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666302/
https://www.ncbi.nlm.nih.gov/pubmed/37993769
http://dx.doi.org/10.1186/s12885-023-11630-7