CREaTor: zero-shot cis-regulatory pattern modeling with attention mechanisms

Linking cis-regulatory sequences to target genes has been a long-standing challenge. In this study, we introduce CREaTor, an attention-based deep neural network designed to model cis-regulatory patterns for genomic elements up to 2 Mb from target genes. Coupled with a training strategy that predicts...

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Detalles Bibliográficos
Autores principales: Li, Yongge, Ju, Fusong, Chen, Zhiyuan, Qu, Yiming, Xia, Huanhuan, He, Liang, Wu, Lijun, Zhu, Jianwei, Shao, Bin, Deng, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666311/
https://www.ncbi.nlm.nih.gov/pubmed/37996959
http://dx.doi.org/10.1186/s13059-023-03103-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666311/
https://www.ncbi.nlm.nih.gov/pubmed/37996959
http://dx.doi.org/10.1186/s13059-023-03103-8

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