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Disrupted cardiac fibroblast BCAA catabolism contributes to diabetic cardiomyopathy via a periostin/NAP1L2/SIRT3 axis
BACKGROUND: Periostin is an extracellular matrix protein that plays a critical role in cell fate determination and tissue remodeling, but the underlying role and mechanism of periostin in diabetic cardiomyopathy (DCM) are far from clear. Thus, we aimed to clarify the mechanistic participation of per...
Autores principales: | Lu, Qing-Bo, Fu, Xiao, Liu, Yao, Wang, Zi-Chao, Liu, Shi-Yi, Li, Yu-Chao, Sun, Hai-Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666354/ https://www.ncbi.nlm.nih.gov/pubmed/37993768 http://dx.doi.org/10.1186/s11658-023-00510-4 |
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