Neuronal SNCA transcription during Lewy body formation

Misfolded α-synuclein (α-syn) is believed to contribute to neurodegeneration in Lewy body disease (LBD) based on considerable evidence including a gene-dosage effect observed in relation to point mutations and multiplication of SNCA in familial Parkinson’s disease. A contradictory concept proposes e...

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Detalles Bibliográficos
Autores principales: Kon, Tomoya, Forrest, Shelley L., Lee, Seojin, Martinez‑Valbuena, Ivan, Li, Jun, Nassir, Nasna, Uddin, Mohammed J., Lang, Anthony E., Kovacs, Gabor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666428/
https://www.ncbi.nlm.nih.gov/pubmed/37996943
http://dx.doi.org/10.1186/s40478-023-01687-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666428/
https://www.ncbi.nlm.nih.gov/pubmed/37996943
http://dx.doi.org/10.1186/s40478-023-01687-7

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