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CDK5: an oncogene or an anti-oncogene: location location location

Recent studies have uncovered various physiological functions of CDK5 in many nonneuronal tissues. Upregulation of CDK5 and/or its activator p35 in neurons promotes healthy neuronal functions, but their overexpression in nonneuronal tissues is causally linked to cancer of many origins. This review f...

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Detalles Bibliográficos
Autores principales: Nikhil, Kumar, Shah, Kavita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666462/
https://www.ncbi.nlm.nih.gov/pubmed/37993880
http://dx.doi.org/10.1186/s12943-023-01895-8