Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration

The causes of nigrostriatal cell death in idiopathic Parkinson’s disease are unknown, but exposure to toxic chemicals may play some role. We followed up here on suggestions that bacterial secondary metabolites might be selectively cytotoxic to dopaminergic neurons. Extracts from Streptomyces venezue...

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Detalles Bibliográficos
Autores principales: Ückert, Anna-Katharina, Rütschlin, Sina, Gutbier, Simon, Wörz, Nathalie Christine, Miah, Mahfuzur R., Martins, Airton C., Hauer, Isa, Holzer, Anna-Katharina, Meyburg, Birthe, Mix, Ann-Kathrin, Hauck, Christof, Aschner, Michael, Böttcher, Thomas, Leist, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666548/
https://www.ncbi.nlm.nih.gov/pubmed/37797477
http://dx.doi.org/10.1016/j.envint.2023.108229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666548/
https://www.ncbi.nlm.nih.gov/pubmed/37797477
http://dx.doi.org/10.1016/j.envint.2023.108229

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