Cargando…

The Interplay Between Splicing of Two Exon Combinations Differentially Affects Membrane Targeting and Function of Human Ca(V)2.2

N-type calcium channels (Ca(V)2.2) are predominantly localized in presynaptic terminals, and are particularly important for pain transmission in the spinal cord. Furthermore, they have multiple isoforms, conferred by alternatively spliced or cassette exons, which are differentially expressed. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Dahimene, Shehrazade, Page, Karen M, Nieto-Rostro, Manuela, Pratt, Wendy S, Dolphin, Annette C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666670/
https://www.ncbi.nlm.nih.gov/pubmed/38020068
http://dx.doi.org/10.1093/function/zqad060