Neutrophil-specific ORAI1 Calcium Channel Inhibition Reduces Pancreatitis-associated Acute Lung Injury

Acute pancreatitis is initiated within pancreatic exocrine cells and sustained by dysregulated systemic inflammatory responses mediated by neutrophils. Store-operated Ca(2+) entry (SOCE) through ORAI1 channels in pancreatic acinar cells triggers acute pancreatitis, and ORAI1 inhibitors ameliorate ex...

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Detalles Bibliográficos
Autores principales: Niu, Mengya, Zhang, Xiuli, Wu, Zengkai, Li, Bin, Bao, Jingpiao, Dai, Juanjuan, Yang, Zihan, Zeng, Yue, Li, Liang, Pandol, Stephen, Sutton, Robert, Wen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666672/
https://www.ncbi.nlm.nih.gov/pubmed/38020066
http://dx.doi.org/10.1093/function/zqad061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666672/
https://www.ncbi.nlm.nih.gov/pubmed/38020066
http://dx.doi.org/10.1093/function/zqad061

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