Cargando…

Optimized peptide nanofibrils as efficient transduction enhancers for in vitro and ex vivo gene transfer

Chimeric antigen receptor (CAR)-T cell therapy is a groundbreaking immunotherapy for cancer. However, the intricate and costly manufacturing process remains a hurdle. Improving the transduction rate is a potential avenue to cut down costs and boost therapeutic efficiency. Peptide nanofibrils (PNFs)...

Descripción completa

Detalles Bibliográficos
Autores principales: Rauch-Wirth, Lena, Renner, Alexander, Kaygisiz, Kübra, Weil, Tatjana, Zimmermann, Laura, Rodriguez-Alfonso, Armando A., Schütz, Desiree, Wiese, Sebastian, Ständker, Ludger, Weil, Tanja, Schmiedel, Dominik, Münch, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666768/
https://www.ncbi.nlm.nih.gov/pubmed/38022685
http://dx.doi.org/10.3389/fimmu.2023.1270243