Activity-based profiling of cullin–RING E3 networks by conformation-specific probes

The cullin–RING ubiquitin ligase (CRL) network comprises over 300 unique complexes that switch from inactive to activated conformations upon site-specific cullin modification by the ubiquitin-like protein NEDD8. Assessing cellular repertoires of activated CRL complexes is critical for understanding...

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Detalles Bibliográficos
Autores principales: Henneberg, Lukas T., Singh, Jaspal, Duda, David M., Baek, Kheewoong, Yanishevski, David, Murray, Peter J., Mann, Matthias, Sidhu, Sachdev S., Schulman, Brenda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667097/
https://www.ncbi.nlm.nih.gov/pubmed/37653169
http://dx.doi.org/10.1038/s41589-023-01392-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667097/
https://www.ncbi.nlm.nih.gov/pubmed/37653169
http://dx.doi.org/10.1038/s41589-023-01392-5

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