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Widespread selenium deficiency in the brain of cases with Huntington's disease presents a new potential therapeutic target

BACKGROUND: Huntington or Huntington's disease (HD) is an autosomal dominant neurodegenerative disease characterised by both progressive motor and cognitive dysfunction; its pathogenic mechanisms remain poorly understood and no treatment can currently slow, stop, or reverse its progression. The...

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Detalles Bibliográficos
Autores principales: Scholefield, Melissa, Patassini, Stefano, Xu, Jingshu, Cooper, Garth J.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667115/
https://www.ncbi.nlm.nih.gov/pubmed/37806287
http://dx.doi.org/10.1016/j.ebiom.2023.104824