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Novel pyrazolothienopyridinones as potential GABA(A) receptor modulators

The synthesis of novel pyrazolothienopyridinone derivatives as potential GABA(A) receptor modulators was performed and is herein described. A crucial step of the synthesis involving handling unstable aminothiophenes was managed via two different synthetic strategies delivering a set of 8 target comp...

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Detalles Bibliográficos
Autores principales: Vega Alanis, Blanca Angelica, Wimmer, Laurin, Ernst, Margot, Schnürch, Michael, Mihovilovic, Marko D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667146/
https://www.ncbi.nlm.nih.gov/pubmed/38020488
http://dx.doi.org/10.1007/s00706-023-03063-6