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Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases

Uncovering the mechanisms regulating hematopoietic specification not only would overcome current limitations related to hematopoietic stem and progenitor cell (HSPC) transplantation, but also advance cellular immunotherapies. However, generating functional human induced pluripotent stem cell (hiPSC)...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaoyi, Barakat, Radwa, Pavani, Giulia, Usha, Masuma Khatun, Calderon, Rodolfo, Snella, Elizabeth, Gorden, Abigail, Zhang, Yudi, Gadue, Paul, French, Deborah L., Dorman, Karin S., Fidanza, Antonella, Campbell, Clyde A., Espin-Palazon, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667254/
https://www.ncbi.nlm.nih.gov/pubmed/37996457
http://dx.doi.org/10.1038/s41467-023-43349-1