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Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases
Uncovering the mechanisms regulating hematopoietic specification not only would overcome current limitations related to hematopoietic stem and progenitor cell (HSPC) transplantation, but also advance cellular immunotherapies. However, generating functional human induced pluripotent stem cell (hiPSC)...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667254/ https://www.ncbi.nlm.nih.gov/pubmed/37996457 http://dx.doi.org/10.1038/s41467-023-43349-1 |