The extrafollicular B cell response is a hallmark of childhood idiopathic nephrotic syndrome

The efficacy of the B cell-targeting drug rituximab (RTX) in childhood idiopathic nephrotic syndrome (INS) suggests that B cells may be implicated in disease pathogenesis. However, B cell characterization in children with INS remains limited. Here, using single-cell RNA sequencing, we demonstrate th...

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Detalles Bibliográficos
Autores principales: Al-Aubodah, Tho-Alfakar, Aoudjit, Lamine, Pascale, Giuseppe, Perinpanayagam, Maneka A., Langlais, David, Bitzan, Martin, Samuel, Susan M., Piccirillo, Ciriaco A., Takano, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667257/
https://www.ncbi.nlm.nih.gov/pubmed/37996443
http://dx.doi.org/10.1038/s41467-023-43504-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667257/
https://www.ncbi.nlm.nih.gov/pubmed/37996443
http://dx.doi.org/10.1038/s41467-023-43504-8

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