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Predicting intratumoral fluid pressure and liposome accumulation using physics informed deep learning

Liposome-based anticancer agents take advantage of the increased vascular permeability and transvascular pressure gradients for selective accumulation in tumors, a phenomenon known as the enhanced permeability and retention(EPR) effect. The EPR effect has motivated the clinical use of nano-therapeut...

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Detalles Bibliográficos
Autores principales: Meaney, Cameron, Stapleton, Shawn, Kohandel, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667280/
https://www.ncbi.nlm.nih.gov/pubmed/37996509
http://dx.doi.org/10.1038/s41598-023-47988-8