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Predicting intratumoral fluid pressure and liposome accumulation using physics informed deep learning
Liposome-based anticancer agents take advantage of the increased vascular permeability and transvascular pressure gradients for selective accumulation in tumors, a phenomenon known as the enhanced permeability and retention(EPR) effect. The EPR effect has motivated the clinical use of nano-therapeut...
Autores principales: | Meaney, Cameron, Stapleton, Shawn, Kohandel, Mohammad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667280/ https://www.ncbi.nlm.nih.gov/pubmed/37996509 http://dx.doi.org/10.1038/s41598-023-47988-8 |
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