The effect of dosage on the protective efficacy of whole-sporozoite formulations for immunization against malaria

Immunization with Plasmodium sporozoites, either attenuated or administered under the cover of an antimalarial drug, can induce strong protection against malaria in pre-clinical murine models, as well as in human trials. Previous studies have suggested that whole-sporozoite (WSpz) formulations based...

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Detalles Bibliográficos
Autores principales: Moita, Diana, Rôla, Catarina, Nunes-Cabaço, Helena, Nogueira, Gonçalo, Maia, Teresa G., Othman, Ahmad Syibli, Franke-Fayard, Blandine, Janse, Chris J., Mendes, António M., Prudêncio, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667361/
https://www.ncbi.nlm.nih.gov/pubmed/37996533
http://dx.doi.org/10.1038/s41541-023-00778-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667361/
https://www.ncbi.nlm.nih.gov/pubmed/37996533
http://dx.doi.org/10.1038/s41541-023-00778-9

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