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Vector-borne Trypanosoma brucei parasites develop in artificial human skin and persist as skin tissue forms

Transmission of Trypanosoma brucei by tsetse flies involves the deposition of the cell cycle-arrested metacyclic life cycle stage into mammalian skin at the site of the fly’s bite. We introduce an advanced human skin equivalent and use tsetse flies to naturally infect the skin with trypanosomes. We...

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Detalles Bibliográficos
Autores principales: Reuter, Christian, Hauf, Laura, Imdahl, Fabian, Sen, Rituparno, Vafadarnejad, Ehsan, Fey, Philipp, Finger, Tamara, Jones, Nicola G., Walles, Heike, Barquist, Lars, Saliba, Antoine-Emmanuel, Groeber-Becker, Florian, Engstler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667367/
https://www.ncbi.nlm.nih.gov/pubmed/37996412
http://dx.doi.org/10.1038/s41467-023-43437-2