Novel synthetic procedures for C2 substituted imidazoquinolines as ligands for the α/β-interface of the GABAA-receptor

A series of substituted imidazoquinolines, a structurally related chemotype to pyrazoloquinolinones, a well-known class of GABA(A) ligands, was prepared via two synthetic procedures and the efficiency of these procedures were compared. One method relies on classical heterocyclic synthesis, the other...

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Detalles Bibliográficos
Autores principales: Draskovits, Markus, Catorci, Daniele, Wimmer, Laurin, Rehman, Sabah, Siebert, David Chan Bodin, Ernst, Margot, Schnürch, Michael, Mihovilovic, Marko D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667396/
https://www.ncbi.nlm.nih.gov/pubmed/38020487
http://dx.doi.org/10.1007/s00706-022-02988-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667396/
https://www.ncbi.nlm.nih.gov/pubmed/38020487
http://dx.doi.org/10.1007/s00706-022-02988-8

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