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Novel synthetic procedures for C2 substituted imidazoquinolines as ligands for the α/β-interface of the GABAA-receptor
A series of substituted imidazoquinolines, a structurally related chemotype to pyrazoloquinolinones, a well-known class of GABA(A) ligands, was prepared via two synthetic procedures and the efficiency of these procedures were compared. One method relies on classical heterocyclic synthesis, the other...
Autores principales: | Draskovits, Markus, Catorci, Daniele, Wimmer, Laurin, Rehman, Sabah, Siebert, David Chan Bodin, Ernst, Margot, Schnürch, Michael, Mihovilovic, Marko D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667396/ https://www.ncbi.nlm.nih.gov/pubmed/38020487 http://dx.doi.org/10.1007/s00706-022-02988-8 |
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