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Case report: Supratherapeutic tacrolimus concentrations with nirmatrelvir/ritonavir in a lung transplant patient: a case report using Rifampin for reversal

Paxlovid (nirmatrelvir/ritonavir) is an antiviral drug used to treat COVID-19, nirmatrelvir, a SARS-CoV-2 main protease inhibitor, works by inhibiting viral replication in the early stages, and ritonavir is a strong cytochrome P450 (CYP) 3A inhibitor that helps the nirmatrelvir reach and maintain th...

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Detalles Bibliográficos
Autores principales: Xiong, Yu, Wang, Xiaoxing, Li, Shu, Zhang, Qian, Guo, Lijuan, Chen, Wenhui, Zhao, Zhixia, Liu, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667419/
https://www.ncbi.nlm.nih.gov/pubmed/38026995
http://dx.doi.org/10.3389/fphar.2023.1285078