Axitinib targets cardiac fibrosis in pressure overload-induced heart failure through VEGFA-KDR pathway

BACKGROUND: There are no specific clinical medications that target cardiac fibrosis in heart failure (HF). Recent studies have shown that tyrosine kinase inhibitors (TKIs) may benefit fibrosis in various organs. However, there is limited research on their application in cardiac fibrosis. Axitinib, a...

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Detalles Bibliográficos
Autores principales: Jiao, Tiantian, Wang, Yuanqi, Lin, Xueqi, Song, Wei, Wang, Liang, Rahman, Tapu Md Sakibur, Xu, Linghao, Nie, Lindong, Zhang, Qi, Li, Jiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667428/
https://www.ncbi.nlm.nih.gov/pubmed/38020087
http://dx.doi.org/10.3389/fmed.2023.1256156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667428/
https://www.ncbi.nlm.nih.gov/pubmed/38020087
http://dx.doi.org/10.3389/fmed.2023.1256156

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