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Suppression of inflammation-induced lung cancer cells proliferation and metastasis by exiguaflavanone A and exiguaflavanone B from Sophora exigua root extract through NLRP3 inflammasome pathway inhibition

Objective: Non-small cell lung cancer (NSCLC) is recognized for its aggressive nature and propensity for high rates of metastasis. The NLRP3 inflammasome pathway plays a vital role in the progression of NSCLC. This study aimed to investigate the effects of S. exigua extract and its active compounds...

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Detalles Bibliográficos
Autores principales: Arjsri, Punnida, Srisawad, Kamonwan, Semmarath, Warathit, Umsumarng, Sonthaya, Rueankham, Lapamas, Saiai, Aroonchai, Rungrojsakul, Methee, Katekunlaphan, Trinnakorn, Anuchapreeda, Songyot, Dejkriengkraikul, Pornngarm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667455/
https://www.ncbi.nlm.nih.gov/pubmed/38026959
http://dx.doi.org/10.3389/fphar.2023.1243727