BioE3 identifies specific substrates of ubiquitin E3 ligases

Hundreds of E3 ligases play a critical role in recognizing specific substrates for modification by ubiquitin (Ub). Separating genuine targets of E3s from E3-interactors remains a challenge. We present BioE3, a powerful approach for matching substrates to Ub E3 ligases of interest. Using BirA-E3 liga...

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Detalles Bibliográficos
Autores principales: Barroso-Gomila, Orhi, Merino-Cacho, Laura, Muratore, Veronica, Perez, Coralia, Taibi, Vincenzo, Maspero, Elena, Azkargorta, Mikel, Iloro, Ibon, Trulsson, Fredrik, Vertegaal, Alfred C. O., Mayor, Ugo, Elortza, Felix, Polo, Simona, Barrio, Rosa, Sutherland, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667490/
https://www.ncbi.nlm.nih.gov/pubmed/37996419
http://dx.doi.org/10.1038/s41467-023-43326-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667490/
https://www.ncbi.nlm.nih.gov/pubmed/37996419
http://dx.doi.org/10.1038/s41467-023-43326-8

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