Development of a diagnostic and risk prediction model for Alzheimer’s disease through integration of single-cell and bulk transcriptomic analysis of glutamine metabolism

BACKGROUND: In this study, we present a novel system for quantifying glutamine metabolism (GM) to enhance the effectiveness of Alzheimer’s disease (AD) diagnosis and risk prediction. METHODS: Single-cell RNA sequencing (scRNA-seq) analysis was utilized to comprehensively assess the expression patter...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Zhao, Tingru, Chu, Xi, Cheng, Zhenyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667556/
https://www.ncbi.nlm.nih.gov/pubmed/38020758
http://dx.doi.org/10.3389/fnagi.2023.1275793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667556/
https://www.ncbi.nlm.nih.gov/pubmed/38020758
http://dx.doi.org/10.3389/fnagi.2023.1275793

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