Cargando…

Synthesis and vectorial functionalisation of pyrazolo[3,4-c]pyridines

Heterocycles are a cornerstone of fragment-based drug discovery (FBDD) due to their prevalence in biologically active compounds. However, novel heterocyclic fragments are only valuable if they can be suitably elaborated to compliment a chosen target protein. Here we describe the synthesis of 5-halo-...

Descripción completa

Detalles Bibliográficos
Autores principales: Bedwell, Elizabeth V., da Silva Emery, Flavio, Clososki, Giuliano C., Steel, Patrick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667592/
https://www.ncbi.nlm.nih.gov/pubmed/38024964
http://dx.doi.org/10.1039/d3ra07458g