Cargando…

Pharmacokinetics and bioequivalence of sunitinib and Sutent(®) in Chinese healthy subjects: an open-label, randomized, crossover study

Purpose: The purpose of this study was to examine the pharmacokinetics (PK), bioequivalence and safety of generic sunitinib and its original product Sutent(®) in healthy Chinese subjects through a phase-I clinical trial. Methods: The study selected two groups of 24 healthy Chinese subjects in a 1:1...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yanli, Deng, Qiaohuan, Gao, Zhenyue, Liu, Guangwen, Su, Zhengjie, Zhao, Yicheng, Zhang, Lixiu, Yang, Haimiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667676/
https://www.ncbi.nlm.nih.gov/pubmed/38026975
http://dx.doi.org/10.3389/fphar.2023.1294688