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Reversible translocation of acyl-CoA:cholesterol acyltransferase (ACAT) between the endoplasmic reticulum and vesicular structures

The enzyme acyl-CoA:cholesterol acyltransferase (ACAT) is normally localized in the endoplasmic reticulum (ER) where it can esterify cholesterol for storage in lipid droplets and/or the formation of lipoproteins. Here, we report that ACAT can translocate from the ER into vesicular structures in resp...

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Detalles Bibliográficos
Autores principales: Schiffmann, Andrea, Ahlswede, Lena, Gimpl, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667705/
https://www.ncbi.nlm.nih.gov/pubmed/38028547
http://dx.doi.org/10.3389/fmolb.2023.1258799