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Regulatory T cells inhibit autoantigen-specific CD4(+) T cell responses in lupus-prone NZB/W F1 mice
INTRODUCTION: Progressive loss of regulatory T cell (Treg)-mediated control over autoreactive effector T cells contributes to the development of systemic lupus erythematosus (SLE). Accordingly, we hypothesized that Treg may also have the capacity to suppress the activation of autoreactive CD4(+) T c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667723/ https://www.ncbi.nlm.nih.gov/pubmed/38022661 http://dx.doi.org/10.3389/fimmu.2023.1254176 |