Regulatory T cells inhibit autoantigen-specific CD4(+) T cell responses in lupus-prone NZB/W F1 mice

INTRODUCTION: Progressive loss of regulatory T cell (Treg)-mediated control over autoreactive effector T cells contributes to the development of systemic lupus erythematosus (SLE). Accordingly, we hypothesized that Treg may also have the capacity to suppress the activation of autoreactive CD4(+) T c...

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Autores principales: Rosenberger, Stefan, Undeutsch, Reinmar, Akbarzadeh, Reza, Ohmes, Justus, Enghard, Philipp, Riemekasten, Gabriela, Humrich, Jens Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667723/
https://www.ncbi.nlm.nih.gov/pubmed/38022661
http://dx.doi.org/10.3389/fimmu.2023.1254176

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