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CD44v6 specific CAR-NK cells for targeted immunotherapy of head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is a major challenge for current therapies. CAR-T cells have shown promising results in blood cancers, however, their effectiveness against solid tumors remains a hurdle. Recently, CD44v6-directed CAR-T cells demonstrated efficacy in controlling tumor gr...

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Detalles Bibliográficos
Autores principales: Ciulean, Ioana Sonya, Fischer, Joe, Quaiser, Andrea, Bach, Christoph, Abken, Hinrich, Tretbar, Uta Sandy, Fricke, Stephan, Koehl, Ulrike, Schmiedel, Dominik, Grunwald, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667728/
https://www.ncbi.nlm.nih.gov/pubmed/38022580
http://dx.doi.org/10.3389/fimmu.2023.1290488