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Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer

BACKGROUND: Cancer cells remodel their local physical environment through processes of matrix reorganisation, deposition, stiffening and degradation. Urokinase-type plasminogen activator (uPA), which is encoded by the PLAU gene, is an extracellular proteolytic enzyme known to be involved in cancer p...

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Detalles Bibliográficos
Autores principales: Micalet, Auxtine, Tappouni, Luke J., Peszko, Katarzyna, Karagianni, Despoina, Lam, Ashley, Counsell, John R., Quezada, Sergio A., Moeendarbary, Emad, Cheema, Umber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667746/
https://www.ncbi.nlm.nih.gov/pubmed/38020586
http://dx.doi.org/10.1016/j.mbplus.2023.100137