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Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer
BACKGROUND: Cancer cells remodel their local physical environment through processes of matrix reorganisation, deposition, stiffening and degradation. Urokinase-type plasminogen activator (uPA), which is encoded by the PLAU gene, is an extracellular proteolytic enzyme known to be involved in cancer p...
Autores principales: | Micalet, Auxtine, Tappouni, Luke J., Peszko, Katarzyna, Karagianni, Despoina, Lam, Ashley, Counsell, John R., Quezada, Sergio A., Moeendarbary, Emad, Cheema, Umber |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667746/ https://www.ncbi.nlm.nih.gov/pubmed/38020586 http://dx.doi.org/10.1016/j.mbplus.2023.100137 |
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