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Actomyosin Activity and Piezo1 Activity Synergistically Drive Urinary System Fibroblast Activation

Mechanical cues play a crucial role in activating myofibroblasts from quiescent fibroblasts during fibrosis, and the stiffness of the extracellular matrix is of significant importance in this process. While intracellular force mediated by myosin II and calcium influx regulated by Piezo1 are the prim...

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Detalles Bibliográficos
Autores principales: Chen, Guo, Gao, Xiaoshuai, Chen, Jiawei, Peng, Liao, Chen, Shuang, Tang, Cai, Dai, Yi, Wei, Qiang, Luo, Deyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667826/
https://www.ncbi.nlm.nih.gov/pubmed/37867255
http://dx.doi.org/10.1002/advs.202303369