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FBXO7 Confers Mesenchymal Properties and Chemoresistance in Glioblastoma by Controlling Rbfox2‐Mediated Alternative Splicing

Mesenchymal glioblastoma (GBM) is highly resistant to radio‐and chemotherapy and correlates with worse survival outcomes in GBM patients; however, the underlying mechanism determining the mesenchymal phenotype remains largely unclear. Herein, it is revealed that FBXO7, a substrate‐recognition compon...

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Detalles Bibliográficos
Autores principales: Li, Shangbiao, Chen, Yanwen, Xie, Yuxin, Zhan, Hongchao, Zeng, Yu, Zeng, Kunlin, Wang, Li, Zhan, Ziling, Li, Cuiying, Zhao, Liqian, Chen, Xiaoxia, Tan, Yujing, Wang, Zhongyong, Bu, Junguo, Song, Ye, Deng, Fan, Zhou, Aidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667838/
https://www.ncbi.nlm.nih.gov/pubmed/37822160
http://dx.doi.org/10.1002/advs.202303561