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Computational study of the motor neuron protein KIF5A to identify nsSNPs, bioactive compounds, and its key regulators

Introduction: Kinesin family member 5A (KIF5A) is a motor neuron protein expressed in neurons and involved in anterograde transportation of organelles, proteins, and RNA. Variations in the KIF5A gene that interfere with axonal transport have emerged as a distinguishing feature in several neurodegene...

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Detalles Bibliográficos
Autores principales: Kumar, Rupesh, Madhavan, Thirumurthy, Ponnusamy, Kalaiarasan, Sohn, Honglae, Haider, Shazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667939/
https://www.ncbi.nlm.nih.gov/pubmed/38028604
http://dx.doi.org/10.3389/fgene.2023.1282234