Genetic background determines severity of Loxl1-mediated systemic and ocular elastosis in mice

Pseudoexfoliation syndrome (PEX) is a systemic, age-related disorder characterized by elastosis and extracellular matrix deposits. Its most significant ocular manifestation is an aggressive form of glaucoma associated with variants in the gene encoding lysyl oxidase-like 1 (LOXL1). Depending upon th...

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Detalles Bibliográficos
Autores principales: Suarez, Maria F., Schmitt, Heather M., Kuhn, Megan S., Watkins, TeddiJo, Hake, Kristyn M., Weisz, Tara, Flynn, Edward J., Elliott, Michael H., Hauser, Michael A., Stamer, W. Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668029/
https://www.ncbi.nlm.nih.gov/pubmed/37905384
http://dx.doi.org/10.1242/dmm.050392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668029/
https://www.ncbi.nlm.nih.gov/pubmed/37905384
http://dx.doi.org/10.1242/dmm.050392

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