A genetic mosaic mouse model illuminates the pre-malignant progression of basal-like breast cancer

Basal-like breast cancer (BLBC) is highly aggressive, and often characterized by BRCA1 and p53 deficiency. Although conventional mouse models enabled the investigation of BLBC at malignant stages, its initiation and pre-malignant progression remain understudied. Here, we leveraged a mouse genetic sy...

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Detalles Bibliográficos
Autores principales: Zeng, Jianhao, Singh, Shambhavi, Zhou, Xian, Jiang, Ying, Casarez, Eli, Atkins, Kristen A., Janes, Kevin A., Zong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668031/
https://www.ncbi.nlm.nih.gov/pubmed/37815460
http://dx.doi.org/10.1242/dmm.050219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668031/
https://www.ncbi.nlm.nih.gov/pubmed/37815460
http://dx.doi.org/10.1242/dmm.050219

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