Elobixibat improves rectal sensation in patients with chronic constipation aged ≥60 years: a randomised placebo-controlled study

OBJECTIVE: High rectal sensory thresholds (RSTs) are associated with chronic constipation (CC), especially in older patients. Bile acids (BAs) affect the RSTs of healthy individuals. Here, we aimed to investigate the effects of the BA transporter inhibitor elobixibat in patients with CC aged ≥60 yea...

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Detalles Bibliográficos
Autores principales: Manabe, Noriaki, Umeyama, Minami, Ishizaki, Sonoko, Ota, Takumi, Kuratani, Shinji, Katsumata, Ryo, Fujita, Minoru, Haruma, Ken, Camilleri, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Neurogastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668193/
https://www.ncbi.nlm.nih.gov/pubmed/37993269
http://dx.doi.org/10.1136/bmjgast-2023-001257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668193/
https://www.ncbi.nlm.nih.gov/pubmed/37993269
http://dx.doi.org/10.1136/bmjgast-2023-001257

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