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Mitochondrial OPA1 Deficiency Is Associated to Reversible Defects in Spatial Memory Related to Adult Neurogenesis in Mice

Mitochondria are integrative hubs central to cellular adaptive pathways. Such pathways are critical in highly differentiated postmitotic neurons, the plasticity of which sustains brain function. Consequently, defects in mitochondria and in their dynamics appear instrumental in neurodegenerative dise...

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Detalles Bibliográficos
Autores principales: Andraini, Trinovita, Moulédous, Lionel, Petsophonsakul, Petnoi, Florian, Cédrick, Gauzin, Sébastien, Botella-Daloyau, Marlène, Arrázola, Macarena, Nikolla, Kamela, Philip, Adam, Leydier, Alice, Marque, Manon, Arnauné-Pelloquin, Laetitia, Belenguer, Pascale, Rampon, Claire, Miquel, Marie-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668243/
https://www.ncbi.nlm.nih.gov/pubmed/37863658
http://dx.doi.org/10.1523/ENEURO.0073-23.2023