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Genotype-guided new approach for dose optimisation of hydroxychloroquine administration in Chinese patients with SLE

OBJECTIVES: The study aims to investigate the impact of gene polymorphisms on blood hydroxychloroquine (HCQ) concentrations in patients with SLE and provide guidelines for individualised care. METHODS: 489 Chinese patients with SLE taking HCQ for more than 3 months were collected in this study. The...

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Detalles Bibliográficos
Autores principales: Xie, Han, Wen, Xin, Wang, Yuchun, Huang, Xuan, Shu, Qing, Wang, Dandan, Geng, Linyu, Jin, Ziyi, Shen, Wei, Ge, Weihong, Zhu, Yizhun, Sun, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668244/
https://www.ncbi.nlm.nih.gov/pubmed/37993281
http://dx.doi.org/10.1136/lupus-2023-000997