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TIE1 and TEK signalling, intraocular pressure, and primary open-angle glaucoma: a Mendelian randomization study

BACKGROUND: In primary open-angle glaucoma (POAG), lowering intraocular pressure (IOP) is the only proven way of slowing vision loss. Schlemm’s canal (SC) is a hybrid vascular and lymphatic vessel that mediates aqueous humour drainage from the anterior ocular chamber. Animal studies support the impo...

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Detalles Bibliográficos
Autores principales: Rajasundaram, Skanda, Zebardast, Nazlee, Mehta, Puja, Khawaja, Anthony P., Warwick, Alasdair, Duchinski, Katherine, Burgess, Stephen, Gill, Dipender, Segrè, Ayellet V., Wiggs, Janey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668387/
https://www.ncbi.nlm.nih.gov/pubmed/37996923
http://dx.doi.org/10.1186/s12967-023-04737-9