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Holothurian triterpene glycoside cucumarioside A(2)-2 induces macrophages activation and polarization in cancer immunotherapy

BACKGROUND: Despite intensive developments of adoptive T cell and NK cell therapies, the efficacy against solid tumors remains elusive. Our study demonstrates that macrophage-based cell therapy could be a potent therapeutic option against solid tumors. METHODS: To this end, we determine the effect o...

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Detalles Bibliográficos
Autores principales: Chuang, Wen-Han, Pislyagin, Evgeny, Lin, Liang-Yu, Menchinskaya, Ekaterina, Chernikov, Oleg, Kozhemyako, Valery, Gorpenchenko, Tatiana, Manzhulo, Igor, Chaikina, Elena, Agafonova, Irina, Silchenko, Alexandra, Avilov, Sergey, Stonik, Valentin, Tzou, Shey-Cherng, Aminin, Dmitry, Wang, Yun-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668486/
https://www.ncbi.nlm.nih.gov/pubmed/38001420
http://dx.doi.org/10.1186/s12935-023-03141-z