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Association of APOE Haplotypes With Common Age-Related Ocular Diseases in 412,171 Individuals

PURPOSE: Apolipoprotein E4 (APOE4), a known risk factor for Alzheimer's disease, has controversially been associated with reduced risk of primary open-angle glaucoma (POAG) and age-related macular degeneration (AMD). Here, we sought to systematically quantify the associations of APOE haplotypes...

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Detalles Bibliográficos
Autores principales: Liuska, Perttu J., Rämö, Joel T., Lemmelä, Susanna, Kaarniranta, Kai, Uusitalo, Hannu, Lahtela, Elisa, Daly, Mark J., Harju, Mika, Palotie, Aarno, Turunen, Joni A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668614/
https://www.ncbi.nlm.nih.gov/pubmed/37988105
http://dx.doi.org/10.1167/iovs.64.14.33